Objective: To study the antioxidant activity Psammosilene tunicoides in vitro. Method: Antioxidant activities of P. tunicoides were evaluated by the 1

1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging

diamonium salt (ABTS) radical scavenging and ferric reducing antioxidant power (FRAP) assay. Results were compared with that of positive controls PG

BHA and BHT. Result: Antioxidant activity of three extracts from P. tunicoides was weaker than that of the positive control PG

BHA and BHA. In the three extracts

Antioxidant activities of ethyl acetate extract was good. ABTS radical scavenging (IC50=40.54 mg·L-1) and ferric reducing antioxidant power 2.42) μmol·g-1] of ethyl acetate extract were strong

followed by the ABTS radical scavenging (IC50=83.38 mg·L-1) and ferric reducing antioxidant power·g-1] of n-butanol extract

petroleum ether extract was the weakest. Conclusion: Ethyl acetate extract of P. tunicoides had strong antioxidant activity.