ZHA Dao-cheng, HE Yong-chao, ZHAO Xia. Optimization Technology of Germinal Coating Agent[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(5): 38-40.
ZHA Dao-cheng, HE Yong-chao, ZHAO Xia. Optimization Technology of Germinal Coating Agent[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(5): 38-40.DOI:
Objective: To select optimum preparation technology and of germinal coating agent and to evaluated its quality control. Method: Optimum extraction technology was optimized by L9(34) orthogonal design experiment with the content of stilbene glucoside as index; with PVA 124as film forming mateial and film-forming time and film quality as indexes
optimized optimum molding technology by orthogonal design test. Result: optimum extraction conditons of germinal coating agent was:refluxing extracted 2 times with 8 times the amount of 70% ethanol for 1.5 h each time;optimum molding process conditions was:extract of traditional Chinese medicine 35 mL
PVA124 7 g
glycerine 2 mL
sodium carboxymethyl cellulose 0.75 g. Conclusion: Preparation technology of this coating agent was reasonable