Objective: To observe the efficiency and safety of triple therapy in the treatment of rheumatism arthritises providing the evidene for the standard treatment of rheumatoid arthritis with traditional Chinese medicine integrated with western medicine. Method: One hundred and twenty patients were randomly divided into treatment group and control group.The treatment group was treated with triple therapy including: ①oral modified angelicae pubescentis andloranthi decoction; ② traditional Chinese medicine fumigation; ③oral salicylazosulfapyridine (SASP). The control group was treated with oral SASP and meloxicam tablets. The treatment course was 3 months for both groups. Before and after treatment

biochemical indices such as erythrocyte sedimentation rate(ESR)

rheumatoid factor (RF)

C-reactive protein(CRP)

and other indicators of improvement. Result: Compared with the control group

the treatment groupcould significantly improve the clinical symptoms and signs (P<0.01)

ESR and CRP also decreased significantly in the two groups after treatment. Conclusion :Triple therapy for treatment of rheumatoid arthritis can achieve the positive efficacy which would be worthy of a wide clinical application.