Objective: To optimize forming technology of Sanyu ointment. Method: Emulsion-type matrix was screened in different ratio;Using appearance and stability as evaluation indexes

forming technology of Sanyu ointment was optimized by orthogonal test. Result: Optimal forming technology was:Took drug concentrated liquid was added triethanolamine

glycerol and ethylparaben heating to 85 ℃ as aqueous phase;Took stearic acid

glyceryl monostearate

liquid paraffin

white vaselin and lanolin heating to melt at 85 ℃as oil phase. Then added oil phase to aqueous phase with small-streams flowing

stirring at a speed of 550 r·min-1 to cool completely. Conclusion: Optimized forming technology was reasonable and feasible

which could produce stable preparation and was suitable for industrial production.