Objective: To optimize extraction and preparation technology for compound abscess plaster. Method: Extraction technology has chosen the content of chlorogenic acid as index

multiple of added water

boiling time

concentration of alcohol precipitation were as test factors by L9(34)orthogonal test.Samples were determined by HPLC.Preparation technology has chosen film-forming and film appearance as index

and taken One-factor test to find out optimum film-coating agent and accessories. Result: Optimum extraction technology was A3B3C1.Optimal preparation technology was PVA-178 811 g

PEG-4 002 mL

concentrated liquid 42 mL

stired

soaked 1 h

dissolved in hot water

then added 42 mL 95% ethanol

2 mL glycerol

1 mL azone

amount of ethylparaben

stired well. Conclusion: This technology was stable with high content of chlorogenic acid. It was compatible in film-forming

appearance and film forming time. This technology could be chosen as optimum extraction technology.