Objective : To find out the occurrence rate of adverse drug reactions (ADR) following the intravenous administration of Xiyanping Injection and to understand the relative factors such as the type and constitution of ADR. To preliminarily explore the methods for reevaluation of the drug after marketing. Method : A comprehensive collection of literature was classified into 3 categories

synchronous clinical study

monitoring of ADR and analysis of medical records

as well as individual or typical case reports. Result: Different study methods indicated that the mean occurrence rate of ADR in Xiyanping Injection was2.02%;ADR manifested mainly as anaphylactic reaction. In addition

a variety of rare types of ADR was discovered

which was not indicated in the instructions of the product. Conclusion: The ADR of Xiyanping injection represented mainly as anaphylactic reaction

especially with anaphylactic shock.