Objective: To study the antipyretic

antinociceptive and anti-inflammatory effects of Huangyu cataplasm (HYC). Method: The antipyretic effects of HYC were observed on febrile animals induced by three kinds of pyrogens including dry yeast

typhoid paratyphoik A

B vaccines

and milk

correspondingly. The analgesic effect was determined by writhing and hot plate tests in mice. Anti-inflammatory action was investigated on the model of paw edema caused by egg white and the pathological model with increasing vascular permeability induced by acetic acid in mice. Result: HYC had good antipyretic effects for experimental fever rabbits induced by dry yeast

typhoid paratyphoik A

B vaccines

and milk heating method. HYC could significantly inhibit the pain responses caused by hot plate and writhing responses induced by acetic acid. HYC could significantly decrease the degree of paw edema caused by egg white in mice and notably inhibit the degree of the increase in permeability of the capillaries. Conclusion: HYC shows considerable antipyretic

analgesic and anti-inflammatory effects