Objective: The recent development on the Radix Isatidis pharmacological action and active substances was summarized. Method: The 45 published articles on Radix Isatidis were reviewed

analyzed

and concluded on the basis of contemporary pharmacology of traditional Chinese medicine. Result: Pharmacological action and active constituent of Radix Isatidis in anti-various

anti-endotoxin

anti-inflammatory and increase immune function has been researched. On this basis

the author put forward a new idea for researching the heat-clearing and detoxicating function of Radix Isatidis. Conclusion: There has been a great research achievement on Radix Isatidis. However

pharmacological action active constituent of heat-clearing and detoxicating function of Radix Isatidis still have no unified understanding. It advises to research Radix Isatidis by multi-channel

multi-mechanism and multi-constituent way.