ZHANG Xin, JIN Feng-yun, LIANG Guang-yi, et al. Comparison the Content of Evodiamine and Rutaecarpine from Compatible Granule, Compound Granule and Traditional Decoction of Zuojin Pills[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(19): 67-71.
ZHANG Xin, JIN Feng-yun, LIANG Guang-yi, et al. Comparison the Content of Evodiamine and Rutaecarpine from Compatible Granule, Compound Granule and Traditional Decoction of Zuojin Pills[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(19): 67-71.DOI:
Objective: To compare the content of evodiamine and rutaecarpine from traditional decoction
compound granules and granule formulation in the Zuojin pills . Method: The content of evodiamine and rutaecarpine in the three forms of Zuojin pills was determined and the method to determine content was established by HPLC. Result: There is 15.455 3 mg·g-1 evodiamine and rutaecarpine in the traditional decoction
21.792 4 mg·g-1 in the compound granules
26.648 3 mg·g-1 in the formulation granules. Conclusion: There are significant differences in the three forms of Zuojin pills. The order is formulation granules>compound granules>traditional decoction.