GUI Man-man, ZHANG Li-feng, LI Xue-yan, et al. Comparison of Immunologic Function of Same Compound Using Astragalus Radix and Using Hedysari Radix[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(21): 203-206.
GUI Man-man, ZHANG Li-feng, LI Xue-yan, et al. Comparison of Immunologic Function of Same Compound Using Astragalus Radix and Using Hedysari Radix[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(21): 203-206.DOI:
Objective: To compare the effects of the same compound (Yiqi Yangxue decoction and Buzhong Yiqi decoction) prescription containing Astragali Radix (AR) and Hedysari Radix (HR)
respectively
on immunologic functions of mice. Method: The sixty mice were divided randomly into six groups:the control group
the model group
Yiqi Yangxue decoction containing AR group
Yiqi Yangxue decoction containing HR group
Buzhong Yiqi decoction containing AR group and Buzhong Yiqi decoction containing HR group. The mice were injected peritoneally with cyclophosphamide to establish immunosuppressive model
and spleen lymphocyte Proliferation
IL-1
IL-4 and serum hemolysin level
NK cells activity were observed Result: Afteradministration
the immunologic functions were significantly increased. The compounds congtaining HR were more significant than compounds containingg AR in spleen lymphocyte proliferation
but in other respects
the two compounds whether congtaining AR or HR had no obvious diffference. Conclusion: Both Yiqi Yangxue decoction and Buzhong Yiqi decoction containg HR are better thancompouds congtaining AR in improving cellular immune function.