Objective: Establish quality method for Yixinshu Capsule. Method: TLC method was used to identify Ginseng

Salvia

Schisandra and Astragalus

the content of ginseng saponins Rg1 and Re was determined by HPLC on Merk RP-using C18 (4.6 mm×250 mm

5 μm) of chromatographic column with acetonitrile-0.05% phosphoric acid (20 ∶80) as mobile phase at 203 nm. Result: TLC spots were clear with strong specificity and easy identification. Ginseng saponins Rg1 was linear in the range of 0.399 2-3.992 0 μg (r=0.999 9)

ginseng saponins Re was linear in the range of 0.395 6-3.956 0 μg (r =0.999 9)

the average recovery of ginseng saponins Rg1 and Re was 99.6%

RSD of 1.9%. Conclusion: This method is accurate

simple

sensitive with good reproducibility

and can more effectively control the quality of Yixinshu capsule by raising the quality standards.