Objective: To observe the therapeutic effect of Yinjia pellet on hyperthyroidism (Grave’s disease) of hyperactive fire due to Yin deficiency. Method: Fifty-four cases according with the diagnostic criteria of hyperthyroidism (Grave’s disease) and syndrome of hyperactive fire due to Yin deficiency simultaneously were divided into two groups at random

Yinjia pellet group and western medicine group

and conducted an observation on therapeutic effect for 3 months. Finally

comparative analysis between pre-therapy and post-therapy was conducted

including clinical symptoms

signs

serum thyroid hormone

thyroid-related antibodies and cytokine. Result: Yinjia pellet group is superior to western medicine group on improving clinical symptoms

signs and serum thyroid hormone. Conclusion: Therapeutic effect of Yinjia pellet on hyperthyroidism (Grave's disease) of hyperactive fire due to Yin deficiency is superior to western medicine.