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纸质出版日期:2011
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孟红旗, 杨安平, 刘雪梅, 等. 健脾平肝法辅助治疗Tourette综合征[J]. 中国实验方剂学杂志, 2011,17(20):272-275.
MENG Hong-qi, YANG An-ping, LIU Xiue-mei, et al. Adjuvant Treatment of Tourette’s Syndrome with Jianpi Pinggan[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(20): 272-275.
目的: 探索Tourette综合征(TS)的中西医结合治疗
以期寻求有效的治疗方法。 方法: 将62例Tourette综合征患者随机分为2组
对照组用氟哌啶醇治疗0.05 g·kg-1·d-1
分3次口服
中西医结合组在健脾平肝的基础上
同时服用氟哌啶醇治疗0.05 g·kg-1·d-1
分3次口服。2个疗程后进行评定。治疗前后使用耶鲁抽动抽动程度综合量表(YGTSS) 及治疗中需处理的不良反应症状量表(TESS) 评估其疗效及不良反应。 结果: 两组比较总有效率有显著差异(P<0.05);两组治疗后TGTSS评分均较治疗前降低
具有显著性差异(P<0.01)。治疗后中西医结合组评分低于对照组
差异有统计意义(P<0.05);中医症候积分两组治疗前后统计均有显著性差异(P<0.01)
治疗后两组比较也有显著性差异(P<0.01)。 结论: 健脾平肝法能提高治疗TS 的疗效。
Objective: To explore therapeutic efficiency of Tourette’s syndrome by therapy of combining traditional Chinese and western medicine. Method: The patients with Tourette’s syndrome were randomly divided into two groups
the control group was orally treated with haloperidol 0.05 g·kg-1·d-1
tid. the integration group of traditional Chinese and western medicine was orally treated with haloperidol 0.05 g·kg-1·d-1
tid on the basis of Jianpi-pinggan After 2 Course of treatment
the yale global tic severity scale(YGTSS) and treatment emergent symptom scale (TESS) were applied to assess the efficacy and adverse reaction of treatment. Result: The total effective rate were significantly different between two groups(P<0.05). TGTSS score for the two groups was lower(P<0.01)compared with prior treatment. For the integration group of traditional Chinese and western medicine score was lower than the control group(P<0.05) after the treatment. For symptoms of Chinese medicine score showed a significantly different after treatment for two groups(P<0.01). After treatment
there are was significant difference between the two groups (P<0.01). Conclusion: Jianpi-pinggan has effects on TS.
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