Objective: To observe clinical efficacy for treatment of acute cellulitis by the self-made dandelion combined Xuebijing topical ointment. Method: The inclusion criteria found 116 cases.The patients were randomly divided into two groups:control group and treatment group(58 cases

each). Two groups were given intravenous antibiotic therapy. Treatment group was given Xuebijing intravenously with topically ointment of dandelion.After a course of 6 d treatment effects were observed. Result: The curative rate of control group was 60.00%

total effective rate was 78.33%;treatment group the curtive rate was 83.33%

total effective rate was 96.67%. Comparison of cure rate

the total effective in the 2 groups was significant(P<0.05). In the 2 groups

before and after treatment symptom scores

CRP

TNF-α

IL-6 and IL-8

showed statistically significant difference compared(P<0.05).The effect of the treatment group was better than that in the control(P<0.05). Conclusion: The dandelion combined Xuebijing topical ointment for treatment of acute cellulitis is effective significantly

the improvement of clinical symptoms is good with effect for regulation of inflammatory cytokines.