CHEN Xiao-bai, WANG Xiao-ping, WEI Min. Effect of Hance on HBsAg and HBeAg in the HepG2.2.15 Cells[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(22): 184-186.
CHEN Xiao-bai, WANG Xiao-ping, WEI Min. Effect of Hance on HBsAg and HBeAg in the HepG2.2.15 Cells[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(22): 184-186.DOI:
Objective: To observe the inhibitive effect of Abrus mollis Hance on HBV. Method: The TC50 and TC0 of A. mollis to the HepG2.2.15 ceils were determined by MTT assay. The effect of 0 five different concentrations of alcohol extract of A. mollis on HBsAg and HBeAg in the HepG2.2.15 cells was determined by ELISA. Result: A. mollis had a inhibiting effect on the HBsAg and HBeAg with maximum inhibition ratio adding up to 33.1% and 40.1%
respectively
in which the affective time was 144 h and the density was 4 g·L-1. Conclusion: A. mollis can significantly inhibit HBV in vitro.