Objective: To accumulate data to stabilize the processing technology of Radix Paeoniae Alba in Bozhou by comparing the effects of different processing methods on the content of the paeoniflorin and the water-soluble extract in Radix Paeoniae Alba in Bozhou. Method: With the paeoniflorin and the water-soluble extract as criteria

the content of the paeoniflorin and the water-soluble extract in Radix Paeoniae Alba in Bozhou with different processing methods are determined by HPLC and the methods of water-soluble extract determination included in Appendix Ⅹ A of China Pharmacopeia 2010 (vol.Ⅰ). The effects of different processing methods on the content of the paeoniflorin and the water-soluble extract in Radix Paeoniae Alba in Bozhou are investigated in the experiment. Result: With regard to the content of the paeoniflorin and the water-soluble extract in Radix Paeoniae Alba in Bozhou with different processing methods

the content of the method of directly drying is higher up to 3.87% than that of the method of scraping and drying after boiling. The content of this method of boiling and drying after scraping is the lowest. Conclusion: The different methods have different effects on the content of the paeoniflorin and the water-soluble extract in Radix Paeoniae Alba in Bozhou

and the highest content is obtained by the method of directly drying.