Objective: To investigate the formulation procedure of Acanthopanax senticosus capsule. Method : The influence of different excipients on the hygroscopicity of the main medicines was investigated by screening the best processing technology conditions and inspecting the critical relative humidity

angle of repose

and bulk density. Result : The main medicines and soluble starch

microcrystalline cellulose were mixed by a ratio of 40 ∶45 ∶15

70% ethanol was added to make materials soft

20 mesh sieve granulation. The angle of repose of the particles was 33.5°

the bulk density 0.38 g ·mL-1

the critical relative humidity 66%. Conclusion : The molding technology is reasonable and can provide reliable basis for large-scale production.