Objective: To investigate the analgesia and anti-inflammatory effects of the extract of Curcuma kwangsiensis S.G.Lee et C.F.Liang(CKG). Method: Kunming mice (22±2) g were divided into 6 groups randomly. Namely physiological saline group

masculine control group

the extract of CKG low dose (8 g·kg-1) and the extract of CKG high dose (16 g·kg-1) groups. The mice were orally given correspondence drug for 7 days in every group. The analgesia effect of CGK was observed by hot-plate procedure and writhing body method.The anti-inflammatory effects were observed by the pinna swelling model of mice

and the cotton ball granuloma model of mice. Result: The ethanol extract and water extract of CKG could increase pain threshold markedly(P<0.01)

the inhibitory rate was 59%

67%

59%

76% accordingly. The ethanol extract of CKG high-dose group could inhibite auricle swelling caused by xylenes in mouse(P<0.05)

the inhibitory rate was 49%. The ethanol extract and water extract of CKG produced obvious anti-inflammatory effects in other animal models of acute or chronic experimental inflammation(P<0.01). Conclusion: CKG has anti-inflammatory and analgesic effects.