Objective: To optimize the process of volatile oils extraction and β-cyclodextrin(β-CD) inclusion from Fructus Citri Sarcodactylis

Rhizoma Alpiniae Officinarum

Cortex Cinnamomi

Fructus Piperis Longi and Radix Aucklandiae of Changweisan Tablets. Method: The study was carried out with single factor and orthogonal design of L9(34). Determine the optimum conditions for volatile oils extraction with the yield of volatile oils extraction as index.Optimize the process of β-CD inclusion with inclusion ratio of volatile oils and recovery ratio of inclusion compounds as comprehensive evaluation index. Result: The optimized extraction process was as follows: Crude herbal materials extracted for 2.5 hours after soaking 1.0 hours with 12 times amount of water. The optimized inclusion conditions were: applied saturated aqueous solution

the proportion of oil to β-CD was 1 ∶8(mL ∶g)

inclusion temperature at 40 ℃

inclusion time was 60 minutes. Conclusion: The optimum extraction process is suitable with high oil-extraction ratio

The inclusion process is reasonable with minimum cost.