Objective: To study the effect of Chang ji’an extract on D-xylose absorption in rats and intestine propelling movement in mice. Method: Seventy SD rats were randomized into 7 groups:control group

model group (induced by Folium Sennae

1 g ·kg-1)

complex glutamine group

berberine hydrochloride tablets group and Chang ji’an extract groups (2.812

1.406

0.703 g ·kg-1). The treatments (ig) were lasted for 7 days. One hundred and fifty four NIH mice were randomized in the groups as the above mentioned. The model of intestine propelling movement was induced by atropine. The doses of Chang ji’an extract were 4.062

2.031

1.016 g ·kg-1accordingly. The treatments (ig) were also lasted for 7 days. D-xylose content in serum was determined to study the effect of Chang ji’an extract on D-xylose absorption in rats administered senna leaf

and charcoal-powder propelling rate was determined to study the effect of Chang ji’an extract on intestine propelling movement stimulated by neostigmine and that inhibited by atropine. Result: The D-xylose content of serum in high

medium and low dose groups was significantly higher than that content in model group(P<0.05);the charcoal powder propelling rate in high

medium and low dose groups was significantly lower than that rate in the two kinds of model groups(P<0.01). Conclusion: Chang ji’an extract has effects on facilitating absorption of small intestine and inhibiting intestine propelling movement.