Objective: To observe the effect of Qihuo Therapy combine with artificial liver. On chronic severe hepatitis patients. Method: Thirty-eight patients with chronic severe hepatitis were randomly divided into 2 groups. The eighteen cases in control group were based on conventional medical treatment and supportive liver application on the basis of a single heavy plasma exchange treatment

on the basis of conventional therapy

twenty patients in the treated group were treated with Qihuo therapy every other day after artificial liver therapy

the therapeutic course for both groups was 14 days.Before and after treatment

and the changes of liver function

intestinal endotoxemia and patients’subjective symptoms were observed. Result: The patients in the treated group abdominal distention

fatigue

mouth pain

chills improved significantly

compared with the control group there were significant differences (P <0.05)

significantly decreased in both groups of patients and bilirubin endotoxin levels

improve blood clotting function

but the treated group improved more significantly (P <0.05)

liver function in both groups was no significant difference. Conclusion: Qihuo therapy is an effective technique which can improve the artificial liver effect on chronic severe hepatitis

and with no adverse reaction.