Objective: To observe the mainly pharmacological effects of Jingdekang Spray. Method :Pharmacological effects of Jingdekang Spray on in vitro antibacterial action. The rat model of vaginitis infected with blastomyces albicans or baeteria were established

then the rats were randomly divided into four groups(10 in each)and two groups were treated with Jingdekang Spray 2.0 g ·kg-1 and 0.5 g ·kg-1(1 mL ·kg-1)

one group was treated with Fuyanping capsule 0.5 g ·kg-1

and the last group was treated with distilled water. The therapeutic effects of Jingdekang Spray on vaginosis rats were observed. The cavia cobaya model of topical pruritus caused by histamine phosphate was used to observe the relieving itching effect of Jingdekang Spray

which were divided as mentioned above. The mouse model of ear swelling induced by croton oil was used to study the antiinfiammatory effect of Jingdekang Spray

which were randomly divided into four groups

10 rats in each group

and two groups of the extender of croton oil in mouse’s ear were treated with Jingdekang Spray 10.0

2.5 g ·kg-1. Result: Jingdekang Spray could inhibit the growth of bacteria which caused vagina infection;restrain the bacterial and mycotic vaginitis evident. The inhibitory rate for bacterial vaginitis was 82.6%. The curative ratio of mycotica vaginitis was 90%. The spray could restrain the pruritus of cavy by histamine phosphate obviously

the inhibitory rate was 51.2%. The inhibitory rate of extender of croton oil in mouse’s ear was 15.8%. Conclusion: Jingdekang Spray has effects of antibacterial

relieve itching and anti-inflammation.