Objective: To investigate drug-induced adverse reactions by analyzing clinical manifestations. Method: Using retrospective methods the clinical drug adverse reactions were analyzed. Result :Based on data of 452 cases

we learnt obviously that the incidence rate in the old is higher than that in the young.The antibiotic drugs account for most adverse reactions

and adverse reactions occur in several systems. The adverse reactions in skin is the highest

while most are slight. Conclusion: Adverse reactions still exist at large in clinic

In order to avoid or reduce the incidence of the reactions

drugs should be used reasonably with caution in patients.