Objective: To explore the impact of Xuesaitong United Batroxobin on serum hsCRP and plasma vWF levels in patients with acute cerebral infarction. Method: Eighty-two patients with acute cerebral infarction were divided into control group (n=41) and treatment group (n=41).Control group patients were treated with Xuesaitong iv injection 20 mL with 250 mL saline once daity for (d 1-d 4).Based on the application of the control group

the treatment group patients were additionally treated with Batroxobin 20 mL in 250 mL normal saline intravenously for d 1

d 3

d 5. The neurological deficit score and plasma vWF levels

serum hsCRP level were observed in this two groups

before treatment and after treatment 7

14 d. Result: The neurological deficit scores were significantly lower in the treatment group and control group

after 7

14 d (P<0.01).Compared with the control group

treatment group decreased more significantly (P<0.01).Compared with that before treatment

plasma vWF and serum hsCRP levels were significantly increased after 7 d (P<0.01)

compared with the control group

treatment group increased more significantly (P<0.01);14 d plasma vWF levels and serum hsCRP levels were significantly lower (P<0.01)

the treatment group decreased more significantly (P<0.01). Conclusion: Xuesaitong United Batroxobin appears to be better than the treatment of acute cerebral infarction by Xuesaitong alone.