Objective: To study formulation and preparation of Gutong film coating tablets. Method: The single-factor method was taken to optimize the pharmaceutical formulations

the content was selected by granule properties

granulating difficulty

angle of repose

degree of surface smoothness

hardness and disintegration. Result: The optimum process was as follows:the weight proportion of dry extraction to starch

lactose and silica powder was 1 ∶0.5 ∶0.4 ∶0.1; the wetting agent was 85% alcohol; through wet-granulating

tabletting and film coating

the Gutong tablets were prepared successfully. Conclusion: The formulation of Gutong film coating tablets is reasonable and the process technical is simple and feasible

which conforms to the general requirements of production.