Objective: To study the anti-inflammatory effects of the extract of Rubus parvifolius. Method: Butanol fraction from R. parvifolius was obtained for the experiments. Kunming mice and SD rats were used as the animals

and the selection of two dosages was 1.0

0.5 g ·kg-1 ig for 7 d. Mice ear inflammatory edema was induced with xylene and rat paw edema was created by injection of carrageenan. The mice or rats were divided into groups including negative control (normal saline)

positive control (dexamethasone) and the group of the extract from R. parvifolius. The swelling degree of mice ear and rat paw edema

and the swelling inhibition effect caused by the extract of R. parvifolius were observed by using method of volume measurement. Result: The swelling degree of auricle inflammation in mice was reduced by the extract from R. parvifolius compared with that of the control group (P<0.05)

and the swelling inhibitive rates were 81.76% and 76.79% in high and low dose group respectively. The foot swelling of rats induced by carrageenan was significantly inhibited by the extract as compared with that in the control group (P<0.05). Conclusion: The extract (total saponins) of R. parvifolius has an obvious anti-inflammatory effect.