Objective: To investigate the protective effect of Taraxaci Herba on alcohol-induced liver injury. Method: The paper studied alcohol-induced liver injury model in mice. The model mice were randomly divided into five groups

including Taraxaci Herba low dose group

Taraxaci Herba medium dose group

Taraxaci Herba high dose group

bifendate group and model group. Every group was respectively treated for 6 weeks with Taraxaci Herba

bifendate or normal saline accordingly. The activities of aspartate transaminase (AST)

alanine transaminase (ALT) in serum

superoxide dismutase(SOD)

glutathione perioxidase (GSH-Px);and the content of malondialdehyde (MDA)

nitrogen monoxide(NO)

TNF-α in liver were investigated. Result: Taraxaci Herba could remarkably resist the increase of ALT

AST in serum( P <0.05-P<0.01)

and decrease MDA

NO

TNF-α level( P <0.05-P<0.01)

and improve SOD activity and GSH-Px level ( P <0.05-P<0.01)

and the differences were statically significant. Conclusion: Taraxact Herba could change inflammatory mediators and cytokines significantly

thereby reducing or preventing related injury for the anti-inflammatory purpose.