Objective: To study the method of enrichment of fumaric alkaloids by using cation resin. Method: Ultraviolet spectrophotometry was used to determine total fumaric alkaloid with exchange capacity as index. Result: The optimum purification condition was as follows: herbs: concentrate solution was about 1 ∶5

herbs: cation resin was about 1 ∶1; flow rate was 2 BV ·h-1

diameter:high of cation resin column was about 1 ∶10; 5 BV of purified water eluted resin column to removed impurities

flow rate was 2 BV ·h-1

4 BV of 70% ethanol as eluent consisted of 5% ammonia

2 BV ·h-1 flow rate washing resin column. Conclusion: The optimum condition was stable and can be used for purification of alkaloids.