Systematic pharmacological evaluation of material basis for the efficacy of Chinese medicine compound is one of the key issues in modernization and internationalization of Chinese medicine. Many researchers have conducted a great deal of research and practice on it in recent years

especially the serum pharmaco-chemistry of traditional Chinese medicine(TCM) research methods attracted widespread attention and has made significant results. Studies on serum pharmaco-chemistry of TCM for the past five years were briefly reviewed. And this article proposes the research method of material basis of traditional Chinese medicine compound based on correlation analysis of metabolism and efficacy

through clarifying the efficacy and pharmaceutical ingredients and metabolites in vivo qualitative and quantitative relationships

case in Jianghuang capsule

to reveal the material basis for efficacy of Chinese medicine.We hope to extend the ideas of research on material basis of traditional Chinese medicine compound.