Reported cases of adverse reaction of Chinese medicine injection has gradually increased. Safety issues for traditional Chinese medicine injection is questioned and unprecedented attention by the government

business

doctors

patients and rest of the society. It is imperative to establish an accurate

early

rapid detection method for Chinese medicine allergic reaction. Screening allergenic substances in traditional Chinese medicine injection by in vivo and in vitro method is reviewed in this paper. These methods can provides a useful reference in exploring the allergen

selecting efficient sensitive detection of allergens

increasing the accuracy to resolve adverse effects of Chinese medicine injections and ensuring the clinical safety of drugs.