XIE Zhen, CHEN Yong, ZENG Hai-sheng, et al. Application of CCD-RSM for Optimization of Total Flavonoids Extraction in [J]. Chinese journal of experimental traditional medical formulae, 2011, 17(12): 27-30.
XIE Zhen, CHEN Yong, ZENG Hai-sheng, et al. Application of CCD-RSM for Optimization of Total Flavonoids Extraction in [J]. Chinese journal of experimental traditional medical formulae, 2011, 17(12): 27-30.DOI:
Objective: To optimize the extracting process of total flavonoids for Urena lobata. Method: Independent variables were ethanol concentration
reflux time
and solvent
dependent variables were extracting rate of total flavonoids. Central composite design and response surface methodology were used to optimize the extracting process. Result: Analysis indicated that the optimum conditions were 55% ethanol
21 min
17 mL solvent for extractable conditions. Conclusion: The optimum process is simple and more convenient for extracting
by which higher total flavonoids content in Urena lobata L.can be obtaind.