Objective: To compare the effects of Typhae Pollen before and after being carbonized on the hemorheological parameters and clotting time in acute blood-stasis model of rats. Method: The SD rats were divided into control

model

Yunnan White Drug-power 0.27 g ·kg-1

water extract solution of Typhae Pollen 1.2 g ·kg-1

carbo water extract solution of Typhae Pollen 1.2 g ·kg-1

carbo power of Typhae Pollen 1.2 g ·kg-1. Except the control group

blood stasis models were established in the rest groups. The hemorheological parameters

the prothrombinase time (PT)

activated partial thromboplastin time (APTT)

thrombin time (TT) and fibrinogen (FIB) were detected in these groups. Result: Typhae Pollen and carbo of Typhae Pollen could decrease the ηb (the viscosity of whole blood) at high shear rate

ESR(erythrocyte sedimentation rate)

K of ESR and rigidity of erythrocyte

which increased in model rats. Carbo of Typhae Pollen could shorten PT. Typhae Pollen and carbo of Typhae Pollen could shorten APTT

decrease FIB

and the potency of Typhae Pollen was stronger than the carbo. Conclusion: TyPhaePollen and carbo of Typhae Pollen showed the effect of invigorating blood and hemostasis by ameliotating the abnormal hemorheological parameters

shorting blood coagulation time

decreasing FIB. The effect of Typhae Pollen carbo on blood clotting was stronger than Typhae Pollen

while the effect of Typhae Pollen on reducing FIB was stronger than the carbo.