Objective: To study the anti-inflammatory and analgesic effects of Qishen Jiangu Granule. Method: Models of xylene-induced mice ear edema

albumin-induced rats paw edema were performed to study the anti-inflammatory effect.Acetic acid-induced writhing and hot-plate test in mice were used to study the analgeic effect. Result: The inhibitory rates of low

medium and high dose of Qishen Jiangu Granule on mice ear edema were 13%

12%

and 16% respectively.Albumin-induced rat paw edema were significantly suppressed by Qishen Jiangu Granule (the medium dose was the optimum one).The writhing time of mice induced by hot plate and acetic acid-induced writhing were remarkably improved in a dose-dependent manner.(The inhibitory rate of which were 18%

39%

93%

73% and 12%

25%

48%

79%). Conclusion: Qishen Jiangu Granule has obvious anti-inflammatory and pain-relieving effect.