ZAO Lin-lin, MA Yan, ZHAO Yuan, et al. Study on Extraction Process for Berberine of Kuolougenwan with Orthogonal Design[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(6): 24-26.
ZAO Lin-lin, MA Yan, ZHAO Yuan, et al. Study on Extraction Process for Berberine of Kuolougenwan with Orthogonal Design[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(6): 24-26.DOI:
Objective: To study the optimized extraction process of berberine hydrochloride
one of the effective parts of Kuolougenwan. Method: An orthogonal experimental design L9(34) test was adopted in this study. And the content of berberine hydrochloride was determined to fit its quality standard
screening out the best method of extraction conditions. Result: The best extracting technical conditions were as follows: 10 times amount of water
extraction for 2 hour and extracted 2 times. Conclusion: The optimized process is simple
fast and feasible with good stability and repeatability.