Objective: To establish the optimized preparation of Simotang dropping pills. Method : The optimum extraction process was selected with Single-factor test and orthogonal

taking difference of pill mass

dissolution and the shape of pill as indicators

and through examing the dropping temperature

dropping speed and external diameter of burette to select the best dropping conditions. Result: The best dropping conditions was that the dropping temperature was at 75 ℃

dropping speed was 30 to 40 drops per minutes

internal and external diameter of burette are 2.0 mm and 5.0 mm. Conclusion: The formulation technology is suitable for industrial production.