均匀设计优选黄连紫草膏中黄连、黄柏、当归水提工艺

刘丽花; 陈天朝; 翟来超

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均匀设计优选黄连紫草膏中黄连、黄柏、当归水提工艺

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- 均匀设计优选黄连紫草膏中黄连、黄柏、当归水提工艺
- Optimization of Water-extracting Process of Coptis,Chinensis Phellodendron and Radix Angelicae by Uniform Design
- 中国实验方剂学杂志 2011年17卷第4期页码：33-35
- 作者机构：
- 作者简介：
- 基金信息：
  
  河南中医学院院级课题(2008kj14)
- DOI：
  中图分类号：
- 纸质出版日期：2011
- 稿件说明：
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刘丽花, 陈天朝, 翟来超. 均匀设计优选黄连紫草膏中黄连、黄柏、当归水提工艺[J]. 中国实验方剂学杂志, 2011,17(4):33-35.

LIU Li-hua, CHEN Tian-chao, ZHAI Lai-chao. Optimization of Water-extracting Process of Coptis,Chinensis Phellodendron and Radix Angelicae by Uniform Design[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(4): 33-35.
刘丽花, 陈天朝, 翟来超. 均匀设计优选黄连紫草膏中黄连、黄柏、当归水提工艺[J]. 中国实验方剂学杂志, 2011,17(4):33-35. DOI：

LIU Li-hua, CHEN Tian-chao, ZHAI Lai-chao. Optimization of Water-extracting Process of Coptis,Chinensis Phellodendron and Radix Angelicae by Uniform Design[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(4): 33-35. DOI：

摘要

目的 :均匀设计优选黄连紫草膏中黄连、黄柏、当归的水提取工艺。方法: 黄连、黄柏、当归采用水回流提取的方法

以盐酸小檗碱含量和干膏得率为指标

考察加水倍数、浸泡时间、提取时间、提取次数4个因素对提取工艺的影响

最终确定黄连、黄柏、当归的最佳水提工艺。结果: 最佳水提工艺为:8倍量的水

浸泡30 min

提取60 min

提取次数为3次。结论: 试验所得结果可为黄连黄柏当归提取工艺的确定和黄连紫草膏的剂型改革提供依据。

Abstract

Objective: Optimization of water extraction process of rhizoma coptidis

cortex phellodendri and angelica was performed by uniform design. Method: Rhizoma coptidis

cortex phellodendri and angelica were extracted with water by reflux.The content of berberine hydrochloride and dry paste were used as index to inspect the influence of water multiple added

immersion time

extraction time and extraction numbers on extraction process

to determine the optimal water extraction technology. Result: The best water extraction technology was as follows:8 times of water

soaking 30 min

extracted for 60 min and extraction three times. Conclusion: The results can provide the basis for determination of water extraction process and the reform of dosage-form.

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