Objective: To compare the influences of Anemarrhenae Rhizoma and the one processed with salt-water on erythrocyte membrane Na+-K+-ATP enzyme activities in rats with hyperthyroidism and yin deficiency

and to clarify the nourishing yin principle by processed Anemarrhenae Rhizoma with salt water. Method: SD rats

half male and half female

were randomly divided into control group

model group

Liuwei Dihuang Wan group(2.2 g ·kg-1)

high dose Anemarrhenae Rhizoma group and the high dose group of Anemarrhenae Rhizoma processed with salt-water (2 g ·kg-1)

low dose Anemarrhenae Rhizoma group and accordingly the one processed with salt-water group(1 g ·kg-1).Each rat was ig given thyroxine liquid 2 mL(1.25 g ·L-1)every morning. Control group was ig given physiological saline. The treatment groups were ig given corresponding liquids(10 mL ·kg-1)each afternoon. Control group and model group was ig given the same volume of saline. Continuous treatment for three weeks and then the activity of erythrocyte membrane Na+-K+-ATP enzyme was determined. Result: Anemarrhenae Rhizoma and the one processed with salt-water could significantly reduce Na+-K +-ATP enzyme activity(P<0.05).In the low dose group

the effect for the one processed with salt-water was better

but the effect of the high dose groups appeared to be on the contrary. Conclusion: Anemarrhenae Rhizoma and the one processed with salt-water both can nourish kidney yin and clear asthenic fever.