Objective: To investigate the wound healing effect of Jintangbao Spray for promoting superficial second degrees burn

as well as anti-inflammatory and analgesic actions. Method: The effect of wound healing was investigated through superficial second degrees burn model in rats and feet burn model in mice. Anti-inflammatory effect was investigated through carrageenan-induced swelling of rat toes. Analgesic effect was investigated through formaldehyde-induced pain in mice. Result: Compared with the model group

Jintangbao Spray could remarkly promote healing of cutis in the trauma with superficial second degrees burn in rats. The pathomorphological evidences of hepatic tissue showed thatJintangbao Spray could remarkably repair cutaneous epidermis injury and the disorganized collagen fiber-bundle of dermis

and promote dermal follicle proliferation

as well as lighten inflammatory cell intiltration. It could significantly reduce water content in the feet burn model in mice

inhibit the carrageenan-induced swelling of rat toes and lighten the pain caused by formaldehyde in mice. Conclusion: Jintangbao Spray can remarkly promote healing of cutis in the trauma and has anti-inflammatory and analgesic effects

and the evidences provide the basis for clinical application of the medicine.