REN Xin-ci, XU Xian-xiang, XU Du-juan, et al. Effects of Saponins on Bone Metabolism of Osteoporotis Rats Induced by Retioic Acid[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(4): 125-127.
REN Xin-ci, XU Xian-xiang, XU Du-juan, et al. Effects of Saponins on Bone Metabolism of Osteoporotis Rats Induced by Retioic Acid[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(4): 125-127.DOI:
Objective: To explore effects of Achyranthes bidentata saponins(ABS)on bone metabolism of rats with osteoporotis induced by retioic acid. Method: ABS was given to rats with osteoporosis induced by retioic acid
at doses of 30
100
300 mg ·kg-1.Calcium (Ca)
phosphorus (P)
alkaline phosphatase (ALP)
bone gla protein (BGP) and hydroxyproline (HOP) were measured and compared with those of model group. Result: ABS could increase levels of Ca and BGP
enhance ALP activity and decrease HOP level. Conclusion: ABS showed effects on improving bone metabolism of osteoporosis induced by retioic acid in rats.