Objective: The ethanol extraction technology for Changan I was investigated with multi-index comprehensive evaluation method. Method: An orthogonal test was adopted in the study.The content of astragaloside Ⅳ and berberine hydrochloride was used as evaluation index.Data processing was carried out with multi-index comprehensive evaluation method for optimizing the extraction condition. Result: The optimized extraction technology for Changan I was as follows:eight times volume of 70% alcohol

1 volume of the Chinese herbal medicines

3 successive reflux extractions for 2 h of each. Conclusion: The optimized extraction technology was rational and the extraction rate of the active components was high.