Objective: To establish the quality standard for Shaoshi Securing capsule. Method: Paeonia lactiflora and Catsia tora were identified by TLC. The content of paeoniflorin in Shaoshi Securing capsule was determined by HPLC. HPLC analytical method was carried out by using a C18 column and a mixture of methanol-water (27 ∶73) as the mobile phase. The detection wavelength was set at 230 nm. Result: Spots obtained from the test solutions had the same color in reference solution and medical material in the same location

and the bland solution had no interference. The calibration curve was linear in the range of 0.074-0.741 μg ( r =0.999 95). The average recovery of sample was 100.7% with RSD of 2.0% ( n =6). Precision of the analytical method was 1.1% ( n =6). Conclusion: In TLC the spots were very clear and specific to identify the herbal medicine in Shaoshi Securing Capsule. HPLC method is simple

quick

high precise and accurate for the quality control of the capsules.