Objective: To investigate the α-glucosidase inhibitory

antioxidant and antibacterial activity of compound recipe of Lobeliae chinese (CRLC). Method: Fractions were eluted by methnol-water in macroporous resin.All the fractions were assayed for the inhibitory activity of α-glucosidase

antioxidant activity and antibacterial activity by the method of 96-microplates

DPPH

ABTS and FRAP

K-B and dilution method respectively. Result: Active fractions were mainly concentrated in the 100%

60% and 40% methanol-water eluent.100% methanol eluent F (IC50=411.50 mg ·L-1) and G (IC50=543.70 mg ·L-1) were higher than that of Acarbose (IC50=1 081.27 mg ·L-1) which was used as positive control on inhibitory activity of α-glucosidase. 100% methanol eluent F (IC50=11.23 mg ·L-1) and G (IC50=10.81 mg ·L-1) had good ABTS free radical scavenging activity

which was slightly lower than that of BHT (IC50=7.47 mg ·L-1)as positive control. 100% methanol eluent G and 60% methanol eluent E had the highest antibacterial of SA

both of MIC were 62.5 μg ·disc-1. Conclusion: Bioactivity on CRLC was assayed for the first time

and it had good α-glucosidase inhibitory activity

antioxidant activity and antibacterial activity.