Objective: To research the effect of Weishu’an Capsule on animal experimental gastric ulcer. Method: The effect of Weishu’an Capsule on three kinds of modles of gastric ulcer was observed. The models included the model of pyloroligation gastric ucler in rats

the model of cautery gastric ulcer induced by acetic acid in rats and the model of reserpineinduced gastric ulcer in mice. Result: As to the pyloroligation gastric ucler

Weishu’an Capsule could restrain the secretion of gastric juice

decrease the total gastric acidity

and restrain the activity of pepsin; as to the cautery gastric ulcer

it could promote the ulcer to be healed; as to the reserpineinduced gastric ulcer

it could restrain the ulcer. Conclusion: Weishu’an Capsule has the obvious effect for preventing and treating the animal experimental gastric ulcer.