Bufonis venenum and bufonis corium have been widely used in the Chinese Traditional Medicine for a long history. To investigate the chemical differences among the bufonis venenum

bufonis corium

and bufonis periostracum

the progress on the chemical constituents in the different medicinal parts from toads

such as venom and skin

was summarized. The chemical constituents mainly included bufadienolides

indole alkaloids

steriods

and etc. More than one hundred bufadienolides and twelve indole alkaliods were reported and 34 references were cited in the present review.