Objective: The solid phase extraction and capillary gas chromatography were introduced for determining 12 organoehiorine and pyrethroid pesticide residues in polygonum orientale. Method: The organochlorine and pyrethroid pesticides were extracted with n-hexane and acetone by ultrasonic method and cleaned up by Florisil solid-phase extraction (SPE) column. Then

the extract was separated by capillary column HP-5(0.32 mm×30 m

0.25 μm) and detected by (electron capture detector

ECD). The internal standards were used for quantitative determination. Result : A mixed standard solution prepared from primary standards of 9 organochlorine and 3 pyrethroid pesticide. The calibration curve for each of 12 organochlorine and pyrethroid pesticide was prepared covering the concentration ranges of 1 to 200 or 5 to 1 000 μg ·L-1. The average recoveries and RSD were in the range of 82.0%-106.8% and 0.2%-7.9％ at three organochlorine and pyrethroid pesticides levels respectively. The limits of detection were 0.15-13 μg ·kg-1. There were no organochlorine and pyrethroid pesticide detected in 15 batches samples. Conclusion : This method was effective

fast and accurate. It has good repeatability and suitable for the analysis of organochlorine and pyrethroid pesticide in polygonum orientale.