Effect of Shenshen Kangxin Drop Pills on ECG,Blood NO and ET,Myocardium TNF- and IL-6 in Myocardial Ischemia of Rat WU Hong-yan,WANG Hu-ping,XIAO Yan-jiao,CHE Min
Effect of Shenshen Kangxin Drop Pills on ECG,Blood NO and ET,Myocardium TNF- and IL-6 in Myocardial Ischemia of Rat WU Hong-yan,WANG Hu-ping,XIAO Yan-jiao,CHE Min[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(16): 152-154.
Effect of Shenshen Kangxin Drop Pills on ECG,Blood NO and ET,Myocardium TNF- and IL-6 in Myocardial Ischemia of Rat WU Hong-yan,WANG Hu-ping,XIAO Yan-jiao,CHE Min[J]. Chinese journal of experimental traditional medical formulae, 2010, 16(16): 152-154.DOI:
Objective: To investigate the therapeutic action and mechanism of Shenshen Kangxin Drop Pills on the Myocardial Ischemia through observing the diversification of ECG of Myocardial Ischemia
blood NO and ET
myocardium TNF-α and IL-6. Method: Acute myocardial ischemia of rat was esfablished by intravenous injection of ISO. Treatment of the droppills(ig) was givenfor 7 d
ECG waveform
NO in blood
ET in blood
TNF-α
IL-6 in myocardium were measured. Result: ST section of Shenshen Kangxin group(low dose
medium dose and high dose respectively) and Tongxinluo Pills group was lower obviously than that of model group.NO went up and ET went down in Shenshen Kangxin group(low dose
medium dose and high dose respectively) and Tongxinluo Pills group.TNF-α went down in Shenshen Kangxin high dose group.IL-6 went down in Shenshen Kangxin high dose group and Tongxinluo Pills group. Conclusion: Shenshen Kangxin Drop Pills can alleviate myocardum ischemia.It may be related to increast in NO and decrease in ET