Objective: To establish quality standard of Mangankang pills. Method: Angelica sinensis

Atractylodis Macrocephalae Rhizoma

Astragali and Bupleurum were identified by TLC.The content of paeoniflorin of Paeonine Radix Alba in the Mangankang pills was determined by HPLC. Result: TLC method was specific for the identification of Angelica sinensis

Atractylodes

Astragalus and Bupleurum

and no interference was found for negatives.Paeoniflorin was linear in the range of 0.058~1.16 μg.The regression equation was Y=1.07×106X-7.78×103(r=0.999 9).The average recovery was 98.6% (n=6

RSD 1.19%). Conclusion: This method is convenient

accurate

higher sensitivity

and can be used for controling the quality of Mangankang pills.