Objective: To determine the trace elements in traditional Chinese Medicine of ophicslcite and its decoction

and the primary speciation analysis on the trace elements of Ophicalcitum. Method: ICP-MS was used to determine the content of 13 trace elements and their primary speciation also been studied. Result: The content of elements in the residue was far more than the content in the solution. The content of elements in original drug was as follows: Mg>Ca>Fe>K>Zn>Mn>Cu

among which Se

Cu

Mo

K were in a higher extraction rate. Conclusion : The mineral medicine decoction extraction rate and the leaching residue ratio were relatively smaller than botanical drug. In ophicslcite

Se

Cu could be considered to be the two largest elements of the role of the drug or the most characteristic elements.