Objective: To optimize the technological conditions for effective compounds of Aucklandia lappa. by microwave-assisted extraction. Method: The microwave extract technology was chosen and optimized by an orthogonal test. The contents of costunolide and dehydrocostuslactone were determined by HPLC. Each influence factor of effective component of A. lappa by the microwave-assisted extraction was observed. Result: The best extraction was obtained with 400 W as the microwave power. Four volume of ethyl alcohol (60%) extracted for four times and each extract last 20 minitues. Conclusion: The microwave extraction technique is bettev than backflow extraction method. with high efficiency and short extraction time.