Objective: The preparation process optimization of microns red Ginseng was performed with detection of ginsenoside. Method: The single factor law on the factors affected red Ginseng microns in diameter screening

particle size distribution to optimize the production of red Ginseng microns optimum technology. The ginsenoside Rg1

Re and Rb1 were determined by HPLC. Result: The best process was as follows: the wind bag length was 20 cm

crushing time 40 min into the charge for a single 500 g; the concent of ginsenoside Rg1

Re

Rb1 were 20.6

17.7

24.1 mg ·g-1 respectively. Ginsenosides from micron Red Ginseng was significantly higher than normal powder and sliced Red Ginseng . Conclusion: Micron Red Ginseng preparation technology was stable. The content determination method established can be used for determination of ginsenosides composition in micron Red Ginseng .